New discoveries may lead to better treatment for Tinnitus.
This exciting discovery from Tenzin Ngodup, Ph.D., could suggest new targets for tinnitus therapies through inhibitory neuronal activation, and insights into new prevention strategies. We thank Les Paul Foundation for making this vital work possible.
Tinnitus is the perception of a phantom sound, commonly known as “ringing in the ears.” It is a highly prevalent condition and in some cases, can significantly impair the quality of life. Unfortunately, the underlying causes of tinnitus are unknown. However, animal and human studies have linked tinnitus with hyperactivity of auditory neurons in the brain.
Specifically, recent studies implicated hyperactivity in the ventral cochlear nucleus (VCN) as a possible source of tinnitus generation. The VCN is one of the first brain structures to receive auditory information from the ears, and electrical activity in the VCN leads to activity in higher auditory centers. Therefore, an increase in the excitability of neurons in the VCN could lead to higher excitability of neurons observed in higher auditory centers.
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Susan E. Terry, Au.D., F-AAA, F-NAP
Doctor of Audiology
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